Pig

Integrating genome‐wide association study with RNA‐seq revealed DBI as a good candidate gene for intramuscular fat content in Beijing black pigs

Abstract
Increasing intramuscular fat content can enhance the sensory quality of meat, including tenderness, juiciness, flavor, and color. Genome-wide association study and RNA-sequencing analysis were used to identify candidate IMF genes in Beijing Black pigs, a popular species among consumers in northern China. Two and three single nucleotide polymorphisms were significantly associated with IMF in SSC13 and SSC15 respectively. Solute carrier family 4 member 7 on SSC13 and insulin induced gene 2 , coiled-coil domain containing 93 , and diazepam binding inhibitor acyl-CoA binding protein...
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Identification of candidate genes related to highland adaptation from multiple Chinese local chicken breeds by whole genome sequencing analysis

3 monthes ago | By Animal Genetics

Abstract
Understanding the genetic mechanism of highland adaptation is of great importance for breeding improvement of Tibetan chickens. Some studies of TBC have identified some candidate genes and pathways from multiple subgroups, but the related genetic mechanisms remain largely unknown. Different genetic backgrounds and the independent genetic basis of highland adaptation make it difficult to identity the selective region of highland adaptation with all TBC samples. In this study, we conducted pre-analysis in a large-scale population to select a TBC subgroup with the purest and highest...
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