Males

Genome‐wide single nucleotide polymorphism array and whole‐genome sequencing reveal the inbreeding progression of Banna minipig inbred line

9 monthes ago   |   By Animal Genetics

Summary
Inbred pigs are promising animal models for biomedical research and xenotransplantation. Established in 1980, the Banna minipig inbred line originated from a sow and its own male offspring. It was selected from a small backcountry minority Lahu village, where records show that no other pig breed has ever been introduced. During the inbreeding process, we perfomed extreme inbreeding over 23 consecutive generations using full-sibling or parent-offspring mating. In order to investigate the inbreeding effects in BMI pigs across generations over the past 40 years, in this study we...
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